Miao Gui Laboratory

In the summer, the GUI lab warmly welcome two postdocs, Jingwei and Liang. They brought new techniques including reproductive biology and artificial intelligence to the lab, which is great! We also welcome Mengxuan, our new PhD student, who has expertise in cryo-ET data processing. Also, congratulations to Ye-Jun for his Nat Commun paper (https://www.nature.com/articles/s41467-026-74801-7), a … Read more

Congratulations to Yuqi Liu, Qi Liu and the whole team on the wonderful achievement in resolving the structure and assembly mechanism of mouse oocyte cytoplasmic lattices. I’m truly proud of this work! After visualizing the cytoskeleton of sperm, we became curious about what the cytoskeleton of the oocyte might look like. This curiosity led us … Read more

Congrats to Qi for his recent publication in Nat Commun. We revealed the function of sperm doublet microtubule-associated Tektin1, Tektin5, DUSP21 and TSSK6. Surprisingly, these proteins have very diserve roles in regulating sperm motility and integrity. We also esteblisehd Tektin1 as a MIVA gene and TSSK6 as a likely MMAF gene. Congratulations to LIU Qi … Read more

On September 22nd, we explored Jingshan and were rewarded with stunning views and delicious local cuisine. The Jingshan Ancient Path (径山古道) proved quite a challenge, yet we successfully reached the mountain top.

Some new lab photos by a prefessional photographer. So cool!

Huge congrats to LIU Qi for his new paper entitled “In situ cryo-electron tomography reveals the progressive biogenesis of basal bodies and cilia in mouse ependymal cells” being published in Nat Commun. This is a wonderful collabration with Qiang and Xueliang. Also super excited that LIU Qi got the Chinese postdoctoral fellowship — his first … Read more

LI Bo left the Gui lab to resume his traditional Chinese medicine career. As the first lab member, Bo has made a great contribution to the lab including lab management and experiments. We wish him all the best in his new adventure.

During the week of Feb 17th, Miao was invited to give a talk titled “Cilia diversity from ultrastructure” at 2025 GRC Cilia, Mucus and Mucociliary Interactions in Pomona, California. It’s really great to meet old friends and make new friends. Interestingly, although I have been in touch with many of them, this is the first … Read more

On September 30th, our lab went for a BOWLING afternoon (as well as other wonderful entertainments) to welcome the beautiful autumn and to celebrate the National Day.

On July 11th, Miao went to Shanghai to attend the ceremony of MIT TR35 China and gave a speech. Surprisely, Qian Wang, a close friend also won this prize and I did not know until I saw Lihong in the ceremony lol. https://mp.weixin.qq.com/s/oDZa9i7YT3g1JucgPoSyCg https://tr35.mittrchina.com/annual-winner?title=2023 https://mp.weixin.qq.com/s/Wq0AvgZa-JGTxrEYBmqv5A